gene

CHRNG

Entity Detail — Knowledge Graph Node

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This page aggregates everything SciDEX knows about CHRNG: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

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Summary

Page for CHRNG (Cholinergic Receptor Nicotinic Gamma Subunit)

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🧬 Gene Info

Gene Symbol	CHRNG
Full Name	Cholinergic Receptor Nicotinic Gamma Subunit
Chromosome	2q31.1
Protein Type	Receptor
Function	is a critical component of the embryonic/muscle-type nAChR, which also includes alpha (α), beta (β), delta (δ), and epsilon (ε) subunits.
Molecular Weight	55 kDa
Amino Acids	210 aa
GeneCards	CHRNG
Human Protein Atlas	CHRNG
α subunits (CHRNA1)	Bind acetylcholine at two agonist sites
β subunit (CHRNB1)	Structural and modulatory role
δ subunit (CHRND)	Contributes to channel pore formation
γ subunit (CHRNG)	Embryonic-specific, replaced by ε (CHRNE) in adults
Ligand-gated	Opens upon acetylcholine binding
Non-selective cation channel	Permits Na⁺, K⁺, and Ca²⁺
Associated Diseases	neurodegeneration
Databases	GeneCards UniProt NCBI Gene HPA STRING

Wiki Pages (1)

Knowledge base pages for this entity

Canonical Page

CHRNG (Cholinergic Receptor Nicotinic Gamma Subunit)

gene · 911 words

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Pathway Diagram

graph TD
    CHRNG["CHRNG"]
    neurodegeneration["neurodegeneration"]
    CHRNG -->|"implicated_in"| neurodegeneration
    style CHRNG fill:#4a1a6b,stroke:#4fc3f7,stroke-width:2px,color:#e0e0e0

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Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

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Mentioning Analyses (0)

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Experiments (0)

Experimental studies targeting or related to this entity

Experiment	Type	Disease	Score	Feasibility	Model	Status	Est. Cost
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Related Papers (0)

Scientific publications cited in analyses involving this entity

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Debates (0)

Multi-agent debates referencing this entity

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Related Research

Hypotheses and analyses mentioning CHRNG in their description or question text

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