| Gene Symbol | CHRNG |
| Full Name | Cholinergic Receptor Nicotinic Gamma Subunit |
| Chromosome | 2q31.1 |
| Protein Type | Receptor |
| Function | is a critical component of the embryonic/muscle-type nAChR, which also includes alpha (α), beta (β), delta (δ), and epsilon (ε) subunits. |
| Molecular Weight | 55 kDa |
| Amino Acids | 210 aa |
| GeneCards | CHRNG |
| Human Protein Atlas | CHRNG |
| α subunits (CHRNA1) | Bind acetylcholine at two agonist sites |
| β subunit (CHRNB1) | Structural and modulatory role |
| δ subunit (CHRND) | Contributes to channel pore formation |
| γ subunit (CHRNG) | Embryonic-specific, replaced by ε (CHRNE) in adults |
| Ligand-gated | Opens upon acetylcholine binding |
| Non-selective cation channel | Permits Na⁺, K⁺, and Ca²⁺ |
| Associated Diseases | neurodegeneration |
| Databases | GeneCardsUniProtNCBI GeneHPASTRING |
No AI portrait yet
No comments yet. Be the first to comment!