Entity Detail โ Knowledge Graph Node
This page aggregates everything SciDEX knows about CLCN6PROTEIN: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
Clc 6 Chloride Channel is an important component in the neurobiology of neurodegenerative diseases. This page provides detailed information about its structure, function, and role in disease processes.
| Gene Symbol | CLCN6PROTEIN |
| Full Name | ClC-6 Chloride Channel |
| Protein Family | CLC chloride channel family |
| Protein Type | Channel |
| Function | is an important component in the neurobiology of neurodegenerative diseases. |
| Primary Expression | Brain (cortex, hippocampus, cerebellum), peripheral tissues |
| Subcellular Localization | Late endosomes, lysosomes (predicted) |
| Molecular Weight | ~87 kDa |
| UniProt ID | P51796 |
| GeneCards | CLCN6PROTEIN |
| Human Protein Atlas | CLCN6PROTEIN |
| Protein Name | ClC-6 Chloride Channel |
| Gene | CLCN6 |
| Channel | Location |
| ClC-3 | Synaptic vesicles |
| Associated Diseases | neurodegeneration |
| Databases | GeneCardsNCBI GeneHPASTRING |
Knowledge base pages for this entity
graph TD
CLCN6PROTEIN["CLCN6PROTEIN"]
neurodegeneration["neurodegeneration"]
CLCN6PROTEIN -->|"implicated_in"| neurodegeneration
style CLCN6PROTEIN fill:#4a1a6b,stroke:#4fc3f7,stroke-width:2px,color:#e0e0e0| Target | Relation | Type | Str |
|---|---|---|---|
| No outgoing edges | |||
| Source | Relation | Type | Str |
|---|---|---|---|
| No incoming edges | |||
Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
|---|---|---|---|
| No targeting hypotheses | |||
Scientific analyses that reference this entity
No analyses mention this entity
Experimental studies targeting or related to this entity
| Experiment | Type | Disease | Score | Feasibility | Model | Status | Est. Cost |
|---|---|---|---|---|---|---|---|
| No experiments found | |||||||
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| No papers found | ||||