gene

COQ8B

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about COQ8B: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

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Summary

Gene encoding a mitochondrial protein kinase essential for coenzyme Q (ubiquinone) biosynthesis, involved in Parkinson's disease and glomerular disease.

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🧬 Gene Info

Gene Symbol	COQ8B
Full Name	Coenzyme Q8B (ADCK4)
Aliases	ubiquinone, COQ8B Protein
Chromosome	19q13.2
Protein Type	Enzyme
Function	encodes a mitochondrial protein essential for coenzyme Q (ubiquinone) biosynthesis.
Molecular Weight	72.4 kDa
Amino Acids	678 aa
UniProt ID	Q9GZX4
NCBI Gene ID	79934
GeneCards	COQ8B
Human Protein Atlas	COQ8B
Associated Diseases	neurodegeneration
Databases	GeneCards HPA STRING

🔮 Predicted Structure: COQ8B — AlphaFold Q9GZX4 Click to expand

AI-predicted structure from AlphaFold | Powered by Mol*

Wiki Pages (2)

Knowledge base pages for this entity

Canonical Page

COQ8B — Coenzyme Q8B (ADCK4)

gene · 1023 words

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COQ8B Protein

protein · 1324 words

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Pathway Diagram

graph TD
    COQ8B["COQ8B"]
    neurodegeneration["neurodegeneration"]
    COQ8B -->|"implicated_in"| neurodegeneration
    style COQ8B fill:#4a1a6b,stroke:#4fc3f7,stroke-width:2px,color:#e0e0e0

Outgoing (0)

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Incoming (0)

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Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

Hypothesis	Score	Disease	Analysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Experiments (0)

Experimental studies targeting or related to this entity

Experiment	Type	Disease	Score	Feasibility	Model	Status	Est. Cost
No experiments found

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMID	Authors	Journal	Year	Citations
No papers found

Debates (0)

Multi-agent debates referencing this entity

No debates reference this entity

Related Research

Hypotheses and analyses mentioning COQ8B in their description or question text

No additional research found