gene

CTSA

Entity Detail — Knowledge Graph Node

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This page aggregates everything SciDEX knows about CTSA: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

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🧬 Gene Info

Gene Symbol	CTSA
Full Name	Cathepsin A (Lysosomal Protective Protein)
Chromosome	20q13.12
Protein Type	Enzyme
Function	CTSA encodes cathepsin A (also called protective protein/cathepsin A, PPCA), a multifunctional lysosomal enzyme with several important functions:
Primary Expression	regions associated with learning and memory, including the hippocampus and cerebral cortex[@demaret2004]
Molecular Weight	46 kDa
Amino Acids	419 aa
Exons	15
UniProt ID	P10619
NCBI Gene ID	2151
Ensembl ID	ENSG00000166664
OMIM	613512
GeneCards	CTSA
Human Protein Atlas	CTSA
Associated Diseases	neurodegeneration
Databases	GeneCards HPA STRING

🔮 Predicted Structure: CTSA — AlphaFold P10619 Click to expand

AI-predicted structure from AlphaFold | Powered by Mol*

Wiki Pages (3)

Knowledge base pages for this entity

Canonical Page

Pathway Diagram

graph TD
    CTSA["CTSA"]
    neurodegeneration["neurodegeneration"]
    CTSA -->|"implicated_in"| neurodegeneration
    style CTSA fill:#4a1a6b,stroke:#4fc3f7,stroke-width:2px,color:#e0e0e0

Outgoing (0)

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Incoming (0)

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Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

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Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Experiments (0)

Experimental studies targeting or related to this entity

Experiment	Type	Disease	Score	Feasibility	Model	Status	Est. Cost
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Related Papers (0)

Scientific publications cited in analyses involving this entity

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Debates (0)

Multi-agent debates referencing this entity

No debates reference this entity

Related Research

Hypotheses and analyses mentioning CTSA in their description or question text

No additional research found