gene

CTSW

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about CTSW: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

0Connections

0Hypotheses

0Analyses

0Outgoing

0Incoming

0Experiments

0Debates

Summary

Page for CTSW (Cathepsin W)

View on Wiki →

No AI portrait yet

🧬 Gene Info

Gene Symbol	CTSW
Full Name	Cathepsin W
Chromosome	19q13.33
Protein Type	Protease
Function	is a member of the papain family of cysteine proteases that is predominantly expressed in cytotoxic lymphocytes, including CD8+ T-cells and natural killer (NK) cells.
Primary Expression	CD8+ T-cells, NK cells, NKT cells
Subcellular Localization	the endoplasmic reticulum (ER) and secretory granules, rather than lysosomes. This unique subcellular localization refle
Molecular Weight	40 kDa
Amino Acids	371 aa
UniProt ID	P27773
NCBI Gene ID	1501
Ensembl ID	ENSG00000141540
OMIM	604168
GeneCards	CTSW
Human Protein Atlas	CTSW
Associated Diseases	Cancer, Immunodeficiency
Databases	GeneCards HPA STRING

🔮 Predicted Structure: CTSW — AlphaFold P27773 Click to expand

AI-predicted structure from AlphaFold | Powered by Mol*

Wiki Pages (1)

Knowledge base pages for this entity

Canonical Page

CTSW (Cathepsin W)

gene · 2084 words

→

Pathway Diagram

graph TD
    CTSW["CTSW"]
    neurodegeneration["neurodegeneration"]
    CTSW -->|"implicated_in"| neurodegeneration
    style CTSW fill:#4a1a6b,stroke:#4fc3f7,stroke-width:2px,color:#e0e0e0

Outgoing (0)

Target	Relation	Type	Str
No outgoing edges

Incoming (0)

Source	Relation	Type	Str
No incoming edges

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

Hypothesis	Score	Disease	Analysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Experiments (0)

Experimental studies targeting or related to this entity

Experiment	Type	Disease	Score	Feasibility	Model	Status	Est. Cost
No experiments found

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMID	Authors	Journal	Year	Citations
No papers found

Debates (0)

Multi-agent debates referencing this entity

No debates reference this entity

Related Research

Hypotheses and analyses mentioning CTSW in their description or question text

No additional research found