concept

CYP2C18

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about CYP2C18: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

22Connections

0Hypotheses

0Analyses

15Outgoing

7Incoming

No summary available yet. View on Wiki →

💡 Concept Info

Name	CYP2C18
Key Genes/Proteins	CYP3A5, GBA3, SLC22A2, COMT, AND, UGT3A1
Related Diseases	Hypertension

Wiki Pages (2)

Knowledge base pages for this entity

slc22a2

gene · 1811 words

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GBA3 — Glucosidase Beta 3

gene · 916 words

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Pathway Diagram

graph TD
    CYP2C18["CYP2C18"]
    CYP2C18 -->|"involved_in"| Metabolic_Processes["Metabolic Processes"]
    CYP2C18 ---|"associated"| Hypertension["Hypertension"]
    CYP2C18 ---|"associated"| CYP3A5["CYP3A5"]
    CYP2C18 ---|"associated"| GBA3["GBA3"]
    CYP2C18 ---|"associated"| SLC22A2["SLC22A2"]
    CYP2C18 ---|"associated"| COMT["COMT"]
    INSULIN_RESISTANCE["INSULIN RESISTANCE"] ---|"associated"| CYP2C18
    UGT3A1["UGT3A1"] ---|"associated"| CYP2C18
    CYP3A5 ---|"associated"| CYP2C18
    GBA3 ---|"associated"| CYP2C18
    COMT ---|"associated"| CYP2C18

Outgoing (15)

Target	Relation	Type	Str
Metabolic Processes	involved_in	process	0.80
Hypertension	associated_with	disease	0.65
CYP3A5	associated_with	gene	0.60
GBA3	associated_with	gene	0.60
SLC22A2	associated_with	gene	0.60
COMT	associated_with	gene	0.60
AND	associated_with	gene	0.60
UGT3A1	associated_with	gene	0.60
INSULIN RESISTANCE	associated_with	gene	0.60
Insulin	associated_with	protein	0.60
App	associated_with	protein	0.60
CYP3A5	interacts_with	gene	0.60
GBA3	interacts_with	gene	0.60
SLC22A2	interacts_with	gene	0.60
UGT3A1	interacts_with	gene	0.60

Incoming (7)

Source	Relation	Type	Str
INSULIN RESISTANCE	associated_with	gene	0.60
UGT3A1	associated_with	gene	0.60
CYP3A5	associated_with	gene	0.60
GBA3	associated_with	gene	0.60
COMT	associated_with	gene	0.60
SLC22A2	associated_with	gene	0.60
COMT	interacts_with	gene	0.60

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

Hypothesis	Score	Disease	Analysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMID	Authors	Journal	Year	Citations
No papers found