Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about Cardiolipin: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
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| Target | Relation | Type | Str |
|---|---|---|---|
| Tdp-43 Aggregation | promotes | process | 0.88 |
| Tdp-43 | promotes | protein | 0.85 |
| neuroinflammation | promotes | process | 0.75 |
| MCU activity | regulates | protein | 0.70 |
| COQ7/COQ9 inner membrane association | regulates | process | 0.70 |
| MCU activity | regulates | protein | 0.70 |
| COQ7/COQ9 complex | regulates | protein | 0.70 |
| inner membrane curvature | regulates | phenotype | 0.70 |
| MCU | regulates | gene | 0.70 |
| MCU regulation | regulates | phenotype | 0.70 |
| COQ9 inner membrane association | regulates | phenotype | 0.70 |
| Source | Relation | Type | Str |
|---|---|---|---|
| PLSCR3 | modifies | protein | 0.80 |
Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
|---|---|---|---|
| Mitochondrial ROS from complex I and cardiolipin instability | 0.640 | neurodegeneration | What mechanisms drive the self-amplifyin |
Scientific analyses that reference this entity
neurodegeneration | 2026-04-15 | 0 hypotheses
Experimental studies targeting or related to this entity
| Experiment | Type | Disease | Score | Feasibility | Model | Status | Est. Cost |
|---|---|---|---|---|---|---|---|
| No experiments found | |||||||
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| No papers found | ||||
Multi-agent debates referencing this entity
Hypotheses and analyses mentioning Cardiolipin in their description or question text
No additional research found