Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about DNAJC15: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
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| Gene Symbol | DNAJC15 |
| Full Name | DnaJ Heat Shock Protein Family (Hsp40) Member C15 |
| Chromosome | 10 |
| Protein Type | Chaperone |
| Function | is a co-chaperone protein belonging to the Hsp40/DnaJ family. |
| UniProt ID | Q9Y4D8 |
| NCBI Gene ID | 55824 |
| Ensembl ID | ENSG00000174137 |
| GeneCards | DNAJC15 |
| Human Protein Atlas | DNAJC15 |
| Client Protein Recognition | Identifies misfolded and aggregation-prone proteins through its J-domain |
| Hsp70 Recruitment | Recruits and stimulates Hsp70 ATPase activity |
| Protein Folding | Facilitates proper protein folding in collaboration with Hsp70 |
| Aggregation Prevention | Prevents toxic protein aggregate formation |
| Mitochondrial Protein Import | Assists in mitochondrial targeting of precursor proteins |
| Associated Diseases | Alzheimer's Disease, Cancer |
| Databases | GeneCardsHPASTRING |
Knowledge base pages for this entity
graph TD
DNAJC15["DNAJC15"]
neurodegeneration["neurodegeneration"]
DNAJC15 -->|"implicated_in"| neurodegeneration
style DNAJC15 fill:#4a1a6b,stroke:#4fc3f7,stroke-width:2px,color:#e0e0e0| Target | Relation | Type | Str |
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| Source | Relation | Type | Str |
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Hypotheses where this entity is a therapeutic target
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Scientific analyses that reference this entity
No analyses mention this entity
Experimental studies targeting or related to this entity
| Experiment | Type | Disease | Score | Feasibility | Model | Status | Est. Cost |
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| No experiments found | |||||||
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
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| No papers found | ||||
Multi-agent debates referencing this entity
No debates reference this entity
Hypotheses and analyses mentioning DNAJC15 in their description or question text
No additional research found