protein

DNAJC3

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about DNAJC3: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

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Summary

Page for DNAJC3 Protein

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🔬 Protein Info

Gene Symbol	DNAJC3
Protein Type	Gene
Function	DNAJC3, also known as P58IPK or ERdj5, is an endoplasmic reticulum (ER)-localized DnaJ chaperone with multiple cellular functions
Primary Expression	tissues with high secretory capacity:
Amino Acids	483 aa
UniProt ID	Q9Y2H1
Ensembl ID	ENSG00000137168
GeneCards	DNAJC3
Human Protein Atlas	DNAJC3
ER protein folding	DNAJC3 assists in protein folding and quality control in the ER
J-domain function	Recruits Hsp70 for protein folding assistance
Associated Diseases	neurodegeneration
Databases	GeneCards NCBI Gene HPA STRING

🔮 Predicted Structure: DNAJC3 — AlphaFold Q9Y2H1 Click to expand

AI-predicted structure from AlphaFold | Powered by Mol*

Wiki Pages (4)

Knowledge base pages for this entity

Canonical Page

Pathway Diagram

graph TD
    DNAJC3["DNAJC3"]
    neurodegeneration["neurodegeneration"]
    DNAJC3 -->|"implicated_in"| neurodegeneration
    style DNAJC3 fill:#4a1a6b,stroke:#4fc3f7,stroke-width:2px,color:#e0e0e0

Outgoing (0)

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Incoming (0)

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Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

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Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Experiments (0)

Experimental studies targeting or related to this entity

Experiment	Type	Disease	Score	Feasibility	Model	Status	Est. Cost
No experiments found

Related Papers (0)

Scientific publications cited in analyses involving this entity

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Debates (0)

Multi-agent debates referencing this entity

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Related Research

Hypotheses and analyses mentioning DNAJC3 in their description or question text

No additional research found