protein

DNML1PROTEIN

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about DNML1PROTEIN: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

0Connections

0Hypotheses

0Analyses

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0Incoming

0Experiments

No summary available yet. View on Wiki →

🔬 Protein Info

Gene Symbol	DNM1L
Full Name	Dynamin 1 Like (Dynamin-Related Protein 1)
Chromosome	12p11.21
Function	DRP1 orchestrates mitochondrial fission
Primary Expression	astrocytes and microglia
Subcellular Localization	Cytosolic, synaptic vesicles, mitochondria
Molecular Weight	~96 kDa
Pathways	Apoptosis, Mitochondrial Function, Mitophagy, Oxidative Stress
UniProt ID	Q05193
NCBI Gene ID	10059
Ensembl ID	ENSG00000087420
GeneCards	DNM1L
Human Protein Atlas	DNM1L
Protein Name	Dynamin-1
Protein Length	864 amino acids
Associated Diseases	AD, ALI, ALS, Aging, Alzheimer
Known Drugs/Compounds	rapamycin, metformin
Interactions	CANX, LGALS3, CALCOCO2, G3BP1, PEX3, SQSTM1
KG Connections	976 knowledge graph edges
Databases	GeneCards HPA STRING

🔮 Predicted Structure: DNML1PROTEIN — AlphaFold Q05193 Click to expand

AI-predicted structure from AlphaFold | Powered by Mol*

Wiki Pages (1)

Knowledge base pages for this entity

Canonical Page

Dynamin-1 Protein

protein · 817 words

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Pathway Diagram

graph TD
    DNML1PROTEIN["DNML1PROTEIN"]
    neurodegeneration["neurodegeneration"]
    DNML1PROTEIN -->|"implicated_in"| neurodegeneration
    style DNML1PROTEIN fill:#4a1a6b,stroke:#4fc3f7,stroke-width:2px,color:#e0e0e0

Outgoing (0)

Target	Relation	Type	Str
No outgoing edges

Incoming (0)

Source	Relation	Type	Str
No incoming edges

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

Hypothesis	Score	Disease	Analysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Experiments (0)

Experimental studies targeting or related to this entity

Experiment	Type	Disease	Score	Feasibility	Model	Status	Est. Cost
No experiments found

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMID	Authors	Journal	Year	Citations
No papers found