DUSP1

protein-coding External Resolution
GeneCards NCBI PubMed

External Info (via mygene)

SymbolDUSP1
Namedual specificity phosphatase 1
Typeprotein-coding
Sourcemygene

Summary

The protein encoded by this gene is a phosphatase with dual specificity for tyrosine and threonine. The encoded protein can dephosphorylate MAP kinase MAPK1/ERK2, which results in its involvement in several cellular processes. This protein appears to play an important role in the human cellular response to environmental stress as well as in the negative regulation of cellular proliferation. Finally, the encoded protein can make some solid tumors resistant to both chemotherapy and radiotherapy, m

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