FLNC

protein-coding External Resolution
GeneCards NCBI PubMed

External Info (via mygene)

SymbolFLNC
Namefilamin C
Typeprotein-coding
Sourcemygene

Summary

This gene encodes one of three related filamin genes, specifically gamma filamin. These filamin proteins crosslink actin filaments into orthogonal networks in cortical cytoplasm and participate in the anchoring of membrane proteins for the actin cytoskeleton. Three functional domains exist in filamin: an N-terminal filamentous actin-binding domain, a C-terminal self-association domain, and a membrane glycoprotein-binding domain. Mutations in this gene are a cause of cardiopathy. Two transcript v

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