gene

GBA2

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about GBA2: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

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0Analyses
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Summary

Page for GBA2 Gene - Glucosylceramidase Beta 2

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🧬 Gene Info
Gene SymbolGBA2
Full NameGlucosylceramidase Beta 2
AliasesPage for GBA2 Gene, Page for GBA2 Protein
Chromosome9q34.2
Protein TypeEnzyme
FunctionGBA2 is a member of the glycoside hydrolase family 4.
Primary Expressionvarious tissues including brain, liver, and testis
Molecular Weight95 kDa
Amino Acids846 aa
UniProt IDQ9HCG6
NCBI Gene ID57733
Ensembl IDENSG00000143633
GeneCardsGBA2
Human Protein AtlasGBA2
Associated Diseasesneurodegeneration
DatabasesGeneCardsHPASTRING
🔮 Predicted Structure: GBA2 — AlphaFold Q9HCG6 Click to expand

AI-predicted structure from AlphaFold | Powered by Mol*

Wiki Pages (18)

Knowledge base pages for this entity

Canonical Page

GBA2 Gene - Glucosylceramidase Beta 2

gene · 676 words

GBA1 Protein (Glucocerebrosidase)

protein · 3125 words

hereditary-spastic-paraplegia

disease · 2618 words

ceramide-sphingolipid-modulation-therapy

therapeutic · 1845 words

GBA Therapy in Parkinson's Disease

mechanism · 1409 words

GBAP1

gene · 1377 words

Pathway Diagram

graph TD
    GBA2["GBA2"]
    neurodegeneration["neurodegeneration"]
    GBA2 -->|"implicated_in"| neurodegeneration
    style GBA2 fill:#4a1a6b,stroke:#4fc3f7,stroke-width:2px,color:#e0e0e0

Outgoing (0)

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No outgoing edges

Incoming (0)

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No incoming edges

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

HypothesisScoreDiseaseAnalysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMIDAuthorsJournalYearCitations
No papers found