gene

GID1

Entity Detail — Knowledge Graph Node

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This page aggregates everything SciDEX knows about GID1: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

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Summary

GID1 Gene

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🧬 Gene Info

Gene Symbol	GID1
Full Name	Glucose-Induced Degradation Deficient 1 Homolog
Chromosome	17p13.2
Protein Type	Ligase
Function	is a critical component of the GID (CTLH) ubiquitin ligase complex, a multisubunit E3 ligase that plays essential roles in protein quality control, metabolic regulation, and cellular homeostasis.
Primary Expression	Brain, Liver, Kidney, Pancreas
UniProt ID	Q9NWV8
NCBI Gene ID	84144
Ensembl ID	ENSG00000131791
OMIM	618023
GeneCards	GID1
Human Protein Atlas	GID1
Yeast (S. cerevisiae)	The GID complex (also called GID complex) consists of GID1, GID2, GID3, GID4, GID5, GID7, GID8, and GID9
Mammals	The mammalian CTLH complex includes GID1 (also known as ARRDC1 or CT16), GID2, GID3, GID4, GID5, GID7, GID8, GID9, and additional subunits including ARMC8, MAEA, and RAMAC
Databases	GeneCards HPA STRING

🔮 Predicted Structure: GID1 — AlphaFold Q9NWV8 Click to expand

AI-predicted structure from AlphaFold | Powered by Mol*

Wiki Pages (1)

Knowledge base pages for this entity

Canonical Page

GID1 Gene

gene · 1422 words

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Pathway Diagram

graph TD
    GID1["GID1"]
    neurodegeneration["neurodegeneration"]
    GID1 -->|"implicated_in"| neurodegeneration
    style GID1 fill:#4a1a6b,stroke:#4fc3f7,stroke-width:2px,color:#e0e0e0

Outgoing (0)

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Incoming (0)

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Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

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No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

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Experiments (0)

Experimental studies targeting or related to this entity

Experiment	Type	Disease	Score	Feasibility	Model	Status	Est. Cost
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Related Papers (0)

Scientific publications cited in analyses involving this entity

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Debates (0)

Multi-agent debates referencing this entity

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Related Research

Hypotheses and analyses mentioning GID1 in their description or question text

No additional research found