gene

GPR78

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about GPR78: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

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Summary

Page for GPR78

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🧬 Gene Info

Gene Symbol	GPR78
Protein Type	Receptor
Function	GPR78 (GPRC5B) is a member of the G protein-coupled receptor, class C, group 5, member B.
Primary Expression	the brain and involved in synaptic transmission and neuronal development[@kroger2011]
Subcellular Localization	synapses and dendritic processes
Pathways	MAPK pathway, PI3K
Ensembl ID	ENSG00000137737
GeneCards	GPR78
Human Protein Atlas	GPR78
Associated Diseases	neurodegeneration
Databases	GeneCards UniProt NCBI Gene HPA STRING

Wiki Pages (2)

Knowledge base pages for this entity

Canonical Page

GPR78

gene · 923 words

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Pathway Diagram

graph TD
    GPR78["GPR78"]
    neurodegeneration["neurodegeneration"]
    GPR78 -->|"implicated_in"| neurodegeneration
    style GPR78 fill:#4a1a6b,stroke:#4fc3f7,stroke-width:2px,color:#e0e0e0

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Incoming (0)

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Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

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Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Experiments (0)

Experimental studies targeting or related to this entity

Experiment	Type	Disease	Score	Feasibility	Model	Status	Est. Cost
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Related Papers (0)

Scientific publications cited in analyses involving this entity

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No papers found