entity

Glutaminase

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about Glutaminase: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

5Connections
1Hypotheses
0Analyses
1Outgoing
2Incoming

Wiki Pages (14)

Knowledge base pages for this entity

Epigenetic Mechanisms in Alzheimer's Disease

mechanism · 3425 words

glutamate

general · 2389 words

GLUL — Glutamine Synthetase

gene · 2324 words

Glutamate Excitotoxicity in Neurodegeneration

mechanism · 2206 words

Glutamatergic Signaling Pathway

mechanism · 1844 words

Outgoing (2)

TargetRelationTypeStr
Ammonia Productioninvolved_inprocess0.90

Incoming (3)

SourceRelationTypeStr
SIRT5interacts_withgene0.90
SIRT5modulatesgene0.90

Targeting Hypotheses (1)

Hypotheses where this entity is a therapeutic target

HypothesisScoreDiseaseAnalysis
Transglutaminase-2 Cross-Linking Inhibition Strategy 0.488 neurodegeneration Protein aggregation cross-seeding across

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Related Papers (10)

Scientific publications cited in analyses involving this entity

Title & PMIDAuthorsJournalYearCitations
TGM2 and implications for human disease: role of alternative splicing. [PMID:23276939] Lai TS, Greenberg CS Front Biosci (Landmark Ed) 2013 1
Transglutaminase 2 modulates inflammatory angiogenesis via vascular endothelial [PMID:40619121] Zhou G, Zhang M, Zheng S, Yang G, Li L e J Adv Res 2026 0
Anti-Proliferative Effects of Resveratrol on Gingival Fibroblasts Derived From A [PMID:41964344] Kara B, Saygun NI, Köse Özkan C, Özgül S J Periodontal Res 2026 0
The Search for a Universal Treatment for Defined and Mixed Pathology Neurodegene [PMID:39769187] O'Day DH International journal of molec 2024 0
[WALANT - Wide Awake Local Anaesthesia No Tourniquet: Complications in elective [PMID:35168268] Wieschollek S, Forster S, Megerle K Handchirurgie, Mikrochirurgie, 2022 0
Calmodulin Binding Domains in Critical Risk Proteins Involved in Neurodegenerati [PMID:36421678] ["O'Day D"] Current issues in molecular bi 2022 0
Urolithin A suppresses high glucose-induced neuronal amyloidogenesis by modulati [PMID:32704090] Lee HJ, Jung YH, Choi GE Cell Death Differ 2021 0
Engineering complex communities by directed evolution. [PMID:33986540] Chang CY, Vila JCC, Bender M, Li R, Mank Nature ecology & evolution 2021 0
Successful Nonoperative Treatment of Osteochondritis Dissecans of the Humeral Ca [PMID:34825100] Tajika T, Kuboi T, Endo F, Hatori Y, Sai Progress in rehabilitation med 2021 0
Dietary Gluten and Neurodegeneration: A Case for Preclinical Studies. [PMID:32751379] Mohan M, Okeoma CM, Sestak K International journal of molec 2020 0