HDAC8

protein-coding External Resolution
GeneCards NCBI PubMed

External Info (via mygene)

SymbolHDAC8
Namehistone deacetylase 8
Typeprotein-coding
Sourcemygene

Summary

Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to class I of the histone deacetylase family. It catalyzes the deacetylation of lysine residues in the histone N-terminal tails and represses transcription in large multiprotein complexes with transcriptional co-repressors. Multiple trans

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