gene

HILPDA

Entity Detail — Knowledge Graph Node

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This page aggregates everything SciDEX knows about HILPDA: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

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Summary

HILPDA gene involved in lipid metabolism and neurodegeneration

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🧬 Gene Info

Gene Symbol	HILPDA
Full Name	Hypoxia Inducible Lipid Droplet Associated Protein
Chromosome	12q13.13
Protein Type	Receptor
Function	is a gene located on chromosome 12q13.13 that encodes a small secreted protein involved in lipid metabolism and cellular stress responses
Primary Expression	Brain cortex, Hippocampus, Hypothalamus, Adipose tissue, Liver
Amino Acids	125 aa
UniProt ID	Q9Y5J5
NCBI Gene ID	29949
Ensembl ID	ENSG00000107317
OMIM	618547
GeneCards	HILPDA
Human Protein Atlas	HILPDA
Lipid droplet regulation	Promotes lipid droplet formation and triglyceride accumulation under hypoxic conditions
Hypoxia response	Activated by HIF-1α (Hypoxia-Inducible Factor 1-alpha) during oxygen deprivation
Databases	GeneCards HPA STRING

🔮 Predicted Structure: HILPDA — AlphaFold Q9Y5J5 Click to expand

AI-predicted structure from AlphaFold | Powered by Mol*

Wiki Pages (1)

Knowledge base pages for this entity

Canonical Page

HILPDA — Hypoxia Inducible Lipid Droplet Associated Protein

gene · 772 words

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Pathway Diagram

graph TD
    HILPDA["HILPDA"]
    neurodegeneration["neurodegeneration"]
    HILPDA -->|"implicated_in"| neurodegeneration
    style HILPDA fill:#4a1a6b,stroke:#4fc3f7,stroke-width:2px,color:#e0e0e0

Outgoing (0)

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Incoming (0)

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Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

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No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

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Experiments (0)

Experimental studies targeting or related to this entity

Experiment	Type	Disease	Score	Feasibility	Model	Status	Est. Cost
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Related Papers (0)

Scientific publications cited in analyses involving this entity

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Debates (0)

Multi-agent debates referencing this entity

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Related Research

Hypotheses and analyses mentioning HILPDA in their description or question text

No additional research found