gene 772 words KG: HILPDA
Contents

HILPDA — Hypoxia Inducible Lipid Droplet Associated Protein

🧬 Gene Info
Gene SymbolHILPDA
Full NameHypoxia Inducible Lipid Droplet Associated Protein
Chromosome12q13.13
Protein TypeReceptor
Functionis a gene located on chromosome 12q13.13 that encodes a small secreted protein involved in lipid metabolism and cellular stress responses
Primary ExpressionBrain cortex, Hippocampus, Hypothalamus, Adipose tissue, Liver
Amino Acids125 aa
UniProt IDQ9Y5J5
NCBI Gene ID29949
Ensembl IDENSG00000107317
OMIM618547
GeneCardsHILPDA
Human Protein AtlasHILPDA
Lipid droplet regulationPromotes lipid droplet formation and triglyceride accumulation under hypoxic conditions
Hypoxia responseActivated by HIF-1α (Hypoxia-Inducible Factor 1-alpha) during oxygen deprivation
DatabasesGeneCardsHPASTRING

No AI portrait yet

Knowledge Graph

Agent Input

💡 Improve this page

🌐 Cross-references

NCBI GeneUniProtGeneCardsWikipediaHGNCEnsembl

Related Hypotheses (7)

Senescence-Associated Myelin Lipid Remodeling
Score: 0.73
Senescence-Induced Lipid Peroxidation Spreading
Score: 0.73
Interfacial Lipid Mimetics to Disrupt Domain Interaction
Score: 0.72
Metabolic Circuit Breaker via Lipid Droplet Modulation
Score: 0.71
Lipid Droplet Dynamics as Phenotype Switches
Score: 0.67
Heat Shock Protein 70 Disaggregase Amplification
Score: 0.62
Serine/Arginine-Rich Protein Kinase Modulation
Score: 0.62

Related Analyses (12)

Astrocyte reactivity subtypes in neurodegeneration
neurodegeneration · archived
Microglia-astrocyte crosstalk amplification loops in neurode
neurodegeneration · archived
TDP-43 phase separation therapeutics for ALS-FTD
neurodegeneration · archived
APOE4 structural biology and therapeutic targeting strategie
neurodegeneration · archived
Senolytic therapy for age-related neurodegeneration
neurodegeneration · archived

Related Experiments (12)

Animal Model Comparison for Neurodegenerative Disease Therap
clinical · proposed · Score: 0.40
Endocannabinoid System Dysfunction Validation in Parkinson's
clinical · proposed · Score: 0.40
Glymphatic-Circadian Axis Enhancement Therapy for Parkinson'
clinical · proposed · Score: 0.40
Gut Microbiome-Derived Metabolites in Alpha-Synuclein Propag
clinical · proposed · Score: 0.40
Neural Oscillation Dysfunction Validation in Parkinson's Dis
clinical · proposed · Score: 0.40

See Also (1)

Neurodegeneration
disease · KG edge: implicated_in

Community Feedback

0 0 upvotes · 0 downvotes
💬 0 comments ⚠ 0 flags ✏ 0 edit suggestions

No comments yet. Be the first to comment!

View all feedback (JSON)

💬 Discussion (Talk page)

Loading comments...
Public annotations (0)Annotate on Hypothes.is →
No public annotations yet.