Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about IARS2: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
| Gene Symbol | IARS2 |
| Full Name | IARS2 — Isoleucyl-tRNA Synthetase 2, Mitochondrial |
| Chromosome | 9q33 |
| Protein Type | Gene |
| Function | is a nuclear-encoded gene located on chromosome 9q33 that encodes a mitochondrial aminoacyl-tRNA synthetase (aaRS). |
| Amino Acids | 842 aa |
| Exons | 23 |
| NCBI Gene ID | Search NCBI |
| GeneCards | IARS2 |
| Human Protein Atlas | IARS2 |
| Associated Diseases | neurodegeneration |
| Databases | GeneCardsUniProtHPASTRING |
Knowledge base pages for this entity
flowchart TD
A["Upstream Regulators"] --> B["IARS2"]
B --> C["Molecular Mechanism"]
C --> D["Cellular Effects"]
D --> E["Pathological Consequences"]| Target | Relation | Type | Str |
|---|---|---|---|
| No outgoing edges | |||
| Source | Relation | Type | Str |
|---|---|---|---|
| No incoming edges | |||
Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
|---|---|---|---|
| No targeting hypotheses | |||
Scientific analyses that reference this entity
No analyses mention this entity
Experimental studies targeting or related to this entity
| Experiment | Type | Disease | Score | Feasibility | Model | Status | Est. Cost |
|---|---|---|---|---|---|---|---|
| No experiments found | |||||||
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| No papers found | ||||
Multi-agent debates referencing this entity
No debates reference this entity