gene 2,210 words KG: IARS2 2026-03-25
kind:genesection:genesstate:published
Contents

IARS2 — Isoleucyl-tRNA Synthetase 2, Mitochondrial

🧬 Gene Info
Gene SymbolIARS2
Full NameIARS2 — Isoleucyl-tRNA Synthetase 2, Mitochondrial
Chromosome9q33
Protein TypeGene
Functionis a nuclear-encoded gene located on chromosome 9q33 that encodes a mitochondrial aminoacyl-tRNA synthetase (aaRS).
Amino Acids842 aa
Exons23
NCBI Gene IDSearch NCBI
GeneCardsIARS2
Human Protein AtlasIARS2
Associated Diseasesneurodegeneration
DatabasesGeneCardsUniProtHPASTRING

Knowledge Graph

Related Hypotheses (18)

Bacterial Enzyme-Mediated Dopamine Precursor Synthesis
Score: 0.36
APOE-Dependent Autophagy Restoration
Score: 0.61
Digital Twin-Guided Metabolic Reprogramming
Score: 0.61
AMPK hypersensitivity in astrocytes creates enhanced mitocho
Score: 0.57
Senescent Cell Mitochondrial DNA Release
Score: 0.54

Related Analyses (11)

Astrocyte reactivity subtypes in neurodegeneration
neurodegeneration · archived
Autophagy-lysosome pathway convergence across neurodegenerat
neurodegeneration · archived
Senolytic therapy for age-related neurodegeneration
neurodegeneration · archived
Neuroinflammation resolution mechanisms and pro-resolving me
neurodegeneration · archived
What are the mechanisms by which gut microbiome dysbiosis in
neurodegeneration · archived

See Also (1)

Neurodegeneration
disease · KG edge: implicated_in