IBA57

protein-coding External Resolution
GeneCards NCBI PubMed

External Info (via mygene)

SymbolIBA57
Nameiron-sulfur cluster assembly factor IBA57
Typeprotein-coding
Sourcemygene

Summary

The protein encoded by this gene localizes to the mitochondrion and is part of the iron-sulfur cluster assembly pathway. The encoded protein functions late in the biosynthesis of mitochondrial 4Fe-4S proteins. Defects in this gene have been associated with autosomal recessive spastic paraplegia-74 and with multiple mitochondrial dysfunctions syndrome-3. Two transcript variants encoding different isoforms have been found for this gene. The smaller isoform is not likely to be localized to the mito

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