gene

INF2

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about INF2: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

6Connections

0Hypotheses

0Analyses

6Outgoing

0Incoming

0Experiments

0Debates

Summary

Page for INF2 (Inverted Formin 2)

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🧬 Gene Info

Gene Symbol	INF2
Full Name	Inverted Formin 2
Chromosome	14q12
Function	INF2 (Inverted Formin 2) is a member of the formin family of actin-nucleating proteins.
Subcellular Localization	signals, with variants localizing to the endoplasmic reticulum (ER) membrane, mitochondrial outer membrane, and cytoplas
Pathways	Metastasis
UniProt ID	[Q9P2R3](https://www.uniprot.org/uniprot/Q9P2R3)
Ensembl ID	ENSG00000126777
GeneCards	INF2
Human Protein Atlas	INF2
Associated Diseases	neurodegeneration
Interactions	AMPK, CANCER, DRP1, MITOCHONDRIA
KG Connections	6 knowledge graph edges
Databases	GeneCards NCBI Gene HPA STRING

Wiki Pages (3)

Knowledge base pages for this entity

Canonical Page

Pathway Diagram

flowchart TD
    INF2(["INF2"])
    OXIDATIVE_STRESS("OXIDATIVE STRESS")
    Cancer["Cancer"]
    AMPK(["AMPK"])
    CANCER(["CANCER"])
    DRP1(["DRP1"])
    MITOCHONDRIA(["MITOCHONDRIA"])
    Metastasis["Metastasis"]
    neurodegeneration["neurodegeneration"]

    INF2 -->|"regulates"| OXIDATIVE_STRESS
    INF2 -->|"activates"| Cancer
    INF2 -->|"activates"| AMPK
    INF2 -->|"activates"| CANCER
    INF2 -->|"activates"| DRP1
    INF2 -->|"activates"| MITOCHONDRIA
    INF2 -->|"activates"| Metastasis
    INF2 -->|"implicated in"| neurodegeneration

    style INF2 fill:#1a237e,stroke:#4fc3f7,stroke-width:3px,color:#fff

Outgoing (6)

Target	Relation	Type	Str
Cancer	activates	disease	0.65
AMPK	activates	gene	0.60
CANCER	activates	gene	0.60
MITOCHONDRIA	activates	gene	0.60
Metastasis	activates	pathway	0.60
DRP1	activates	gene	0.60

Incoming (0)

Source	Relation	Type	Str
No incoming edges

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

Hypothesis	Score	Disease	Analysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Experiments (0)

Experimental studies targeting or related to this entity

Experiment	Type	Disease	Score	Feasibility	Model	Status	Est. Cost
No experiments found

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMID	Authors	Journal	Year	Citations
No papers found

Debates (0)

Multi-agent debates referencing this entity

No debates reference this entity

Related Research

Hypotheses and analyses mentioning INF2 in their description or question text

No additional research found