Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about KCNMB2: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
| Gene Symbol | KCNMB2 |
| Full Name | Potassium calcium-activated channel subfamily M regulatory beta subunit 2 |
| Chromosome | 3q26.32 |
| Function | The BK channel is encoded by KCNMA1 and requires association with beta subunits for proper function |
| Primary Expression | the central nervous system where they play critical roles in neuronal excitability, neurotransmitter release, and protection against excitotoxic cell |
| UniProt ID | Q9Y5W6 |
| NCBI Gene ID | 10242 |
| Ensembl ID | ENSG00000171388 |
| GeneCards | KCNMB2 |
| Human Protein Atlas | KCNMB2 |
| Protein Name | Calcium-activated potassium channel subunit beta-2 |
| Associated Diseases | neurodegeneration |
| Databases | GeneCardsHPASTRING |
Knowledge base pages for this entity
graph TD
KCNMB2["KCNMB2"]
neurodegeneration["neurodegeneration"]
KCNMB2 -->|"implicated_in"| neurodegeneration
style KCNMB2 fill:#4a1a6b,stroke:#4fc3f7,stroke-width:2px,color:#e0e0e0| Target | Relation | Type | Str |
|---|---|---|---|
| No outgoing edges | |||
| Source | Relation | Type | Str |
|---|---|---|---|
| No incoming edges | |||
Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
|---|---|---|---|
| No targeting hypotheses | |||
Scientific analyses that reference this entity
No analyses mention this entity
Experimental studies targeting or related to this entity
| Experiment | Type | Disease | Score | Feasibility | Model | Status | Est. Cost |
|---|---|---|---|---|---|---|---|
| No experiments found | |||||||
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| No papers found | ||||