gene

KCTD7

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about KCTD7: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

5Connections

0Hypotheses

0Analyses

5Outgoing

0Incoming

0Experiments

0Debates

Summary

Page for KCTD7 Gene (CLN14)

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🧬 Gene Info

Gene Symbol	KCTD7
Full Name	Potassium Channel Tetramerization Domain 7
Aliases	CLN14
Chromosome	7q11.21
Protein Type	Channel
Function	is a gene located on chromosome 7q11.
Primary Expression	neurons and localizes to synaptic terminals:
Molecular Weight	32 kDa
Amino Acids	289 aa
UniProt ID	[Q0VG02](https://www.uniprot.org/uniprot/Q0VG02)
Ensembl ID	ENSG00000143357
OMIM	611725
GeneCards	KCTD7
Human Protein Atlas	KCTD7
Associated Diseases	neurodegeneration
Interactions	RNA
KG Connections	5 knowledge graph edges
Databases	GeneCards NCBI Gene HPA STRING

Wiki Pages (2)

Knowledge base pages for this entity

Canonical Page

KCTD7 Gene (CLN14)

gene · 847 words

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KCTD7 Protein

protein · 1188 words

→

Pathway Diagram

graph TD
    KCTD7["KCTD7"]
    TREM2["TREM2"]
    KCTD7 -->|"associated with"| TREM2
    microglia["microglia"]
    KCTD7 -->|"expressed in"| microglia
    neurodegeneration["neurodegeneration"]
    KCTD7 -->|"implicated in"| neurodegeneration
    style KCTD7 fill:#1a237e,stroke:#4fc3f7,color:#4fc3f7

Outgoing (5)

Target	Relation	Type	Str
microglia	expressed_in	cell_type	0.80
TREM2	associated_with	gene	0.80
RNA	interacts_with	gene	0.60
oxidative stress response	participates_in	pathway	0.60
neurons	expressed_in	cell_type	0.60

Incoming (0)

Source	Relation	Type	Str
No incoming edges

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

Hypothesis	Score	Disease	Analysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Experiments (0)

Experimental studies targeting or related to this entity

Experiment	Type	Disease	Score	Feasibility	Model	Status	Est. Cost
No experiments found

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMID	Authors	Journal	Year	Citations
No papers found

Debates (0)

Multi-agent debates referencing this entity

No debates reference this entity

Related Research

Hypotheses and analyses mentioning KCTD7 in their description or question text

No additional research found