gene

KIF27

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about KIF27: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

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Summary

Page for KIF27 — Kinesin Family Member 27

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🧬 Gene Info

Gene Symbol	KIF27
Full Name	Kinesin Family Member 27
Chromosome	3p14.3
Function	As a member of the kinesin-4 family, KIF27 shares structural features with other kinesin-4 proteins including a motor domain, coiled-coil regions for protein-protein interactions, and a tail domain fo
UniProt ID	[Q86X29](https://www.uniprot.org/uniprot/Q86X29)
Ensembl ID	ENSG00000135426
OMIM	606924
GeneCards	KIF27
Human Protein Atlas	KIF27
Alzheimer's Disease	Hedgehog signaling alterations have been reported in AD models, and KIF27's role in this pathway suggests possible involvement in amyloid processing and neuronal survival
Parkinson's Disease	Ciliary dysfunction is increasingly recognized in PD pathogenesis, and KIF27's ciliary localization positions it as a potential contributor
Huntington's Disease	Hedgehog pathway modifications have been observed in HD models
Associated Diseases	neurodegeneration
Databases	GeneCards NCBI Gene HPA STRING

Wiki Pages (2)

Knowledge base pages for this entity

Canonical Page

KIF27 — Kinesin Family Member 27

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Pathway Diagram

graph TD
    KIF27["KIF27"]
    neurodegeneration["neurodegeneration"]
    KIF27 -->|"implicated_in"| neurodegeneration
    style KIF27 fill:#4a1a6b,stroke:#4fc3f7,stroke-width:2px,color:#e0e0e0

Outgoing (0)

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Incoming (0)

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Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

Hypothesis	Score	Disease	Analysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Experiments (0)

Experimental studies targeting or related to this entity

Experiment	Type	Disease	Score	Feasibility	Model	Status	Est. Cost
No experiments found

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMID	Authors	Journal	Year	Citations
No papers found