gene 978 words KG: KIF27 2026-03-24
kind:genesection:genesstate:published
Contents

KIF27 — Kinesin Family Member 27

🧬 Gene Info
Gene SymbolKIF27
Full NameKinesin Family Member 27
Chromosome3p14.3
FunctionAs a member of the kinesin-4 family, KIF27 shares structural features with other kinesin-4 proteins including a motor domain, coiled-coil regions for protein-protein interactions, and a tail domain fo
UniProt ID[Q86X29](https://www.uniprot.org/uniprot/Q86X29)
Ensembl IDENSG00000135426
OMIM606924
GeneCardsKIF27
Human Protein AtlasKIF27
Alzheimer's DiseaseHedgehog signaling alterations have been reported in AD models, and KIF27's role in this pathway suggests possible involvement in amyloid processing and neuronal survival
Parkinson's DiseaseCiliary dysfunction is increasingly recognized in PD pathogenesis, and KIF27's ciliary localization positions it as a potential contributor
Huntington's DiseaseHedgehog pathway modifications have been observed in HD models
Associated Diseasesneurodegeneration
DatabasesGeneCardsNCBI GeneHPASTRING

Knowledge Graph