Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about M2 macrophage polarization: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
No AI portrait yet
| Target | Relation | Type | Str |
|---|---|---|---|
| No outgoing edges | |||
| Source | Relation | Type | Str |
|---|---|---|---|
| NUPR1 | promotes | gene | 0.95 |
| S1P1 | associated_with | receptor | 0.90 |
| AMPK | activates | protein | 0.90 |
| C1q | regulates | protein | 0.70 |
| C1q | activates | protein | 0.70 |
| AQP3 | enhances | gene | 0.60 |
| GLP-1R agonists | promotes | drug | 0.50 |
| IL-10 | regulates | protein | 0.50 |
| GLP-1R agonists | activates | drug | 0.50 |
Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
|---|---|---|---|
| No targeting hypotheses | |||
Scientific analyses that reference this entity
molecular biology | 2026-04-17 | 10 hypotheses Top: 0.445
neurodegeneration | 2026-04-15 | 2 hypotheses Top: 0.699
Experimental studies targeting or related to this entity
| Experiment | Type | Disease | Score | Feasibility | Model | Status | Est. Cost |
|---|---|---|---|---|---|---|---|
| No experiments found | |||||||
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| No papers found | ||||
Multi-agent debates referencing this entity
closed · Rounds: 4 · Score: 1.00 · 2026-04-19
closed · Rounds: 4 · Score: 0.50 · 2026-04-18
closed · Rounds: 4 · Score: 0.95 · 2026-04-15
Hypotheses and analyses mentioning M2 macrophage polarization in their description or question text
No additional research found