Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about MAFB: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
| Gene Symbol | MAFB |
| Full Name | MAF BZIP Transcription Factor B |
| Aliases | Page for MAFB Gene, Page for MAFB Protein |
| Chromosome | 20q12 |
| Protein Type | Transcription Factor |
| Function | MAFB is a transcription factor of the MAF family that regulates gene expression in glial cells and neurons. |
| Molecular Weight | 41 kDa |
| UniProt ID | Q9Y441 |
| NCBI Gene ID | 7818 |
| Ensembl ID | ENSG00000104140 |
| GeneCards | MAFB |
| Human Protein Atlas | MAFB |
| Cell Type | Expression |
| Microglia | High |
| Oligodendrocytes | High |
| Associated Diseases | Multiple Sclerosis |
| KG Connections | 2 knowledge graph edges |
| Databases | GeneCardsHPASTRING |
Knowledge base pages for this entity
graph TD
MAFB["MAFB"]
Multiple_Sclerosis["Multiple Sclerosis"]
MAFB -->|"associated with"| Multiple_Sclerosis
C1Q["C1Q"]
MAFB -->|"regulates"| C1Q
neurodegeneration["neurodegeneration"]
MAFB -->|"implicated in"| neurodegeneration
style MAFB fill:#1a237e,stroke:#4fc3f7,color:#4fc3f7| Target | Relation | Type | Str |
|---|---|---|---|
| Multiple Sclerosis | associated_with | disease | 0.65 |
| C1Q | regulates | protein | 0.64 |
| Source | Relation | Type | Str |
|---|---|---|---|
| No incoming edges | |||
Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
|---|---|---|---|
| No targeting hypotheses | |||
Scientific analyses that reference this entity
No analyses mention this entity
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| No papers found | ||||