Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about MTCH1: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
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| Gene Symbol | MTCH1 |
| Full Name | Mitochondrial Carrier Homolog 1 |
| Chromosome | 17p12 |
| Function | MTCH1 (Mitochondrial Carrier Homolog 1) is a nuclear-encoded mitochondrial protein that plays a critical role in mitochondrial metabolism and apoptosis regulation. |
| Primary Expression | both neurons and glial cells, with particular emphasis in regions susceptible to neurodegeneration |
| Molecular Weight | 33 kDa |
| UniProt ID | [Q9Y3C5](https://www.uniprot.org/uniprot/Q9Y3C5) |
| Ensembl ID | ENSG00000108389 |
| OMIM | 612317 |
| GeneCards | MTCH1 |
| Human Protein Atlas | MTCH1 |
| Associated Diseases | neurodegeneration |
| Databases | GeneCardsNCBI GeneHPASTRING |
Knowledge base pages for this entity
graph TD
MTCH1["MTCH1"]
neurodegeneration["neurodegeneration"]
MTCH1 -->|"implicated_in"| neurodegeneration
style MTCH1 fill:#4a1a6b,stroke:#4fc3f7,stroke-width:2px,color:#e0e0e0| Target | Relation | Type | Str |
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Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
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Scientific analyses that reference this entity
No analyses mention this entity
Experimental studies targeting or related to this entity
| Experiment | Type | Disease | Score | Feasibility | Model | Status | Est. Cost |
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| No experiments found | |||||||
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
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Multi-agent debates referencing this entity
No debates reference this entity
Hypotheses and analyses mentioning MTCH1 in their description or question text
No additional research found