gene 636 words KG: MTCH1 2026-03-24
kind:genesection:genesstate:published
Contents

MTCH1 — Mitochondrial Carrier Homolog 1

🧬 Gene Info
Gene SymbolMTCH1
Full NameMitochondrial Carrier Homolog 1
Chromosome17p12
FunctionMTCH1 (Mitochondrial Carrier Homolog 1) is a nuclear-encoded mitochondrial protein that plays a critical role in mitochondrial metabolism and apoptosis regulation.
Primary Expressionboth neurons and glial cells, with particular emphasis in regions susceptible to neurodegeneration
Molecular Weight33 kDa
UniProt ID[Q9Y3C5](https://www.uniprot.org/uniprot/Q9Y3C5)
Ensembl IDENSG00000108389
OMIM612317
GeneCardsMTCH1
Human Protein AtlasMTCH1
Associated Diseasesneurodegeneration
DatabasesGeneCardsNCBI GeneHPASTRING

Knowledge Graph

Related Hypotheses (13)

AMPK hypersensitivity in astrocytes creates enhanced mitocho
Score: 0.79
Senescent Cell Mitochondrial DNA Release
Score: 0.74
Near-infrared light therapy stimulates COX4-dependent mitoch
Score: 0.74
TFAM overexpression creates mitochondrial donor-recipient gr
Score: 0.73
Mitochondrial Transfer Pathway Enhancement
Score: 0.70

Related Analyses (10)

Astrocyte reactivity subtypes in neurodegeneration
neurodegeneration · archived
Autophagy-lysosome pathway convergence across neurodegenerat
neurodegeneration · archived
Senolytic therapy for age-related neurodegeneration
neurodegeneration · archived
Neuroinflammation resolution mechanisms and pro-resolving me
neurodegeneration · archived
RNA binding protein dysregulation across ALS FTD and AD
neurodegeneration · archived

Related Experiments (1)

ER-Golgi Secretory Pathway Dysfunction in PD - Experiment De
clinical · proposed · Score: 0.40

See Also (1)

Neurodegeneration
disease · KG edge: implicated_in

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