Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about NAD+/NADH Ratio: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
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| Target | Relation | Type | Str |
|---|---|---|---|
| SIRT1 activity | modulates | process | 0.90 |
| Growth Arrest | causes | phenotype | 0.85 |
| AMPK | regulates | protein | 0.85 |
| Growth Arrest | regulates | process | 0.85 |
| Il-1-Associated Senescence-Associated Secretory Phenotype | inhibits | phenotype | 0.80 |
| Sirtuin-Targeting Therapies | biomarker_for | therapeutic | 0.50 |
| Source | Relation | Type | Str |
|---|---|---|---|
| Mitochondrial Dysfunction | downregulates | process | 0.90 |
| 29184484 | increases | paper | 0.60 |
Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
|---|---|---|---|
| No targeting hypotheses | |||
Scientific analyses that reference this entity
neurodegeneration | 2026-04-04 | 9 hypotheses Top: 0.779
translational neuroscience | 2026-04-04 | 7 hypotheses Top: 0.829
Experimental studies targeting or related to this entity
| Experiment | Type | Disease | Score | Feasibility | Model | Status | Est. Cost |
|---|---|---|---|---|---|---|---|
| No experiments found | |||||||
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| No papers found | ||||
Multi-agent debates referencing this entity
closed · Rounds: 4 · Score: 0.46 · 2026-04-27
closed · Rounds: 4 · Score: 0.46 · 2026-04-27
closed · Rounds: 4 · Score: 0.95 · 2026-04-10
closed · Rounds: 4 · Score: 0.92 · 2026-04-04
Hypotheses and analyses mentioning NAD+/NADH Ratio in their description or question text
No additional research found