gene

NDUFAF8

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about NDUFAF8: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

0Connections

0Hypotheses

0Analyses

0Outgoing

0Incoming

0Experiments

0Debates

Summary

NDUFAF8 is a mitochondrial complex I assembly factor essential for NADH dehydrogenase biogenesis and implicated in Leigh syndrome and Parkinson's disease

View on Wiki →

No AI portrait yet

🧬 Gene Info

Gene Symbol	NDUFAF8
Full Name	NADH Dehydrogenase Complex Assembly Factor 8
Chromosome	19q13.42
Function	encodes a mitochondrial complex I assembly factor that plays a critical role in the biogenesis of the NADH dehydrogenase (complex I) of the mitochondrial respiratory chain.
Molecular Weight	24 kDa
Amino Acids	213 aa
Exons	5
UniProt ID	Q6ZMC2
NCBI Gene ID	285154
Ensembl ID	ENSG00000156437
OMIM	618198
GeneCards	NDUFAF8
Human Protein Atlas	NDUFAF8
Associated Diseases	Parkinson's disease
Databases	GeneCards HPA STRING

🔮 Predicted Structure: NDUFAF8 — AlphaFold Q6ZMC2 Click to expand

AI-predicted structure from AlphaFold | Powered by Mol*

Wiki Pages (1)

Knowledge base pages for this entity

Canonical Page

NDUFAF8 Gene (NADH Dehydrogenase Complex Assembly Factor 8)

gene · 1333 words

→

Pathway Diagram

graph TD
    NDUFAF8["NDUFAF8"]
    neurodegeneration["neurodegeneration"]
    NDUFAF8 -->|"implicated_in"| neurodegeneration
    style NDUFAF8 fill:#4a1a6b,stroke:#4fc3f7,stroke-width:2px,color:#e0e0e0

Outgoing (0)

Target	Relation	Type	Str
No outgoing edges

Incoming (0)

Source	Relation	Type	Str
No incoming edges

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

Hypothesis	Score	Disease	Analysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Experiments (0)

Experimental studies targeting or related to this entity

Experiment	Type	Disease	Score	Feasibility	Model	Status	Est. Cost
No experiments found

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMID	Authors	Journal	Year	Citations
No papers found

Debates (0)

Multi-agent debates referencing this entity

No debates reference this entity

Related Research

Hypotheses and analyses mentioning NDUFAF8 in their description or question text

No additional research found