Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about OPRD1: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
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| Gene Symbol | OPRD1 |
| Full Name | Delta-Opioid Receptor |
| Protein Type | Receptor |
| Function | is an important component in the neurobiology of neurodegenerative diseases. |
| Amino Acids | 372 aa |
| Pathways | MAPK pathway, PI3K, MAPK |
| Ensembl ID | ENSG00000116381 |
| GeneCards | OPRD1 |
| Human Protein Atlas | OPRD1 |
| Associated Diseases | Alzheimer's Disease, Anorexia, Heroin Dependence, Opioid Addiction |
| Interactions | OPRM1 |
| KG Connections | 6 knowledge graph edges |
| Databases | GeneCardsUniProtNCBI GeneHPASTRING |
Knowledge base pages for this entity
flowchart TD
OPRD1(["OPRD1"])
Opioid_Addiction["Opioid Addiction"]
Alzheimer_s_Disease["Alzheimer's Disease"]
Heroin_Dependence["Heroin Dependence"]
Promoter_Methylation["Promoter Methylation"]
OPRM1(["OPRM1"])
Anorexia["Anorexia"]
neurodegeneration["neurodegeneration"]
OPRD1 -->|"associated with"| Opioid_Addiction
OPRD1 -->|"associated with"| Alzheimer_s_Disease
OPRD1 -->|"associated with"| Heroin_Dependence
OPRD1 -->|"upregulates"| Promoter_Methylation
OPRM1 -->|"interacts with"| OPRD1
OPRD1 -->|"associated with"| Anorexia
OPRD1 -->|"implicated in"| neurodegeneration
style OPRD1 fill:#1a237e,stroke:#4fc3f7,stroke-width:3px,color:#fff| Target | Relation | Type | Str |
|---|---|---|---|
| Opioid Addiction | associated_with | disease | 0.80 |
| Heroin Dependence | associated_with | disease | 0.80 |
| Promoter Methylation | upregulates | mechanism | 0.80 |
| Alzheimer's Disease | associated_with | disease | 0.80 |
| Anorexia | associated_with | disease | 0.60 |
| Source | Relation | Type | Str |
|---|---|---|---|
| OPRM1 | interacts_with | gene | 0.80 |
Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
|---|---|---|---|
| No targeting hypotheses | |||
Scientific analyses that reference this entity
No analyses mention this entity
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| No papers found | ||||