Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about OBESTATIN: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
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| Name | OBESTATIN |
| Related Diseases | Glucocorticoid-Induced Muscle Cell Atrophy, Glucocorticoid-Induced Muscle Atrophy, Muscle Cell Atrophy |
| Related Pathways | Ubiquitin-Proteasome System, Autophagy-Lysosome System, ubiquitin-proteasome system, autophagy-lysosome system |
Knowledge base pages for this entity
graph TD
OBESTATIN["OBESTATIN"]
OBESTATIN -->|"interacts"| GPR39["GPR39"]
OBESTATIN -->|"regulates"| Ubiquitin_Proteasome_System["Ubiquitin-Proteasome System"]
OBESTATIN -.protects against.-> Glucocorticoid_Induced_Muscle_["Glucocorticoid-Induced Muscle Cell Atrophy"]
OBESTATIN -->|"regulates"| Autophagy_Lysosome_System["Autophagy-Lysosome System"]
OBESTATIN -->|"modulates"| Skeletal_Muscle["Skeletal Muscle"]| Target | Relation | Type | Str |
|---|---|---|---|
| GPR39 | interacts_with | receptor | 0.95 |
| Glucocorticoid-Induced Muscle Cell Atrophy | protects_against | disease | 0.90 |
| GPR39 | binds | receptor | 0.90 |
| Skeletal Muscle | modulates | cell_type | 0.88 |
| Ubiquitin-Proteasome System | regulates | pathway | 0.85 |
| Autophagy-Lysosome System | regulates | pathway | 0.85 |
| Glucocorticoid-Induced Muscle Atrophy | protects_against | disease | 0.85 |
| Ubiquitin-Proteasome System | modulates | pathway | 0.85 |
| Autophagy-Lysosome System | modulates | pathway | 0.85 |
| Muscle Cell Atrophy | protects_against | phenotype | 0.85 |
| Skeletal Muscle | expressed_in | cell_type | 0.80 |
| Anabolic Effects | mediates | process | 0.80 |
| ubiquitin-proteasome system | controls | pathway | 0.80 |
| autophagy-lysosome system | controls | pathway | 0.80 |
| Source | Relation | Type | Str |
|---|---|---|---|
| No incoming edges | |||
Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
|---|---|---|---|
| No targeting hypotheses | |||
Scientific analyses that reference this entity
No analyses mention this entity
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| No papers found | ||||