Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about SKELETAL MUSCLE: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
No summary available yet. View on Wiki →
No AI portrait yet
| Name | SKELETAL MUSCLE |
Knowledge base pages for this entity
graph TD
SKELETAL_MUSCLE[SKELETAL MUSCLE]
SKELETAL_MUSCLE -->|target for| Amyotrophic_Lateral_Sclerosis[Amyotrophic Lateral Sclerosis]
SKELETAL_MUSCLE -->|regulates| neuroinflammation[neuroinflammation]
SKELETAL_MUSCLE -->|involved_in| ALS[ALS]
AMPK[AMPK] -->|expressed in| SKELETAL_MUSCLE
DUX4[DUX4] -->|expressed in| SKELETAL_MUSCLE
OBESTATIN[OBESTATIN] -->|modulates| SKELETAL_MUSCLE
OBST[OBST] -->|expressed in| SKELETAL_MUSCLE
STAT3[STAT3] -->|expressed in| SKELETAL_MUSCLE
Oligonucleotide_Transport_Vehi[Oligonucleotide Transport Vehicle] -->|targets| SKELETAL_MUSCLE
Autophagic_Defects[Autophagic Defects] -->|expressed in| SKELETAL_MUSCLE
TARDBP[TARDBP] -->|expressed in| SKELETAL_MUSCLE
FUS[FUS] -->|expressed in| SKELETAL_MUSCLE
oleuropein[oleuropein] -->|targets| SKELETAL_MUSCLE| Target | Relation | Type | Str |
|---|---|---|---|
| Amyotrophic Lateral Sclerosis | therapeutic_target | disease | 0.93 |
| neuroinflammation | regulates | process | 0.90 |
| ALS | involved_in | disease | 0.88 |
| Muscle Fibers | associated_with | cell_type | 0.70 |
| Source | Relation | Type | Str |
|---|---|---|---|
| AMPK | expressed_in | protein | 0.90 |
| DUX4 | expressed_in | gene | 0.90 |
| Aging | associated_with | process | 0.90 |
| OBESTATIN | modulates | protein | 0.88 |
| OBST | expressed_in | protein | 0.85 |
| STAT3 | expressed_in | gene | 0.85 |
| Oligonucleotide Transport Vehicle | targets | drug | 0.80 |
| Autophagic Defects | expressed_in | mechanism | 0.80 |
| TARDBP | expressed_in | gene | 0.80 |
| FUS | expressed_in | gene | 0.80 |
| oleuropein | targets | compound | 0.80 |
| LAMP2 | expressed_in | protein | 0.80 |
| OBESTATIN | expressed_in | protein | 0.80 |
| TREM2 | modulates | gene | 0.65 |
| DMPK | expressed_in | gene | 0.60 |
Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
|---|---|---|---|
| No targeting hypotheses | |||
Scientific analyses that reference this entity
No analyses mention this entity
Experimental studies targeting or related to this entity
| Experiment | Type | Disease | Score | Feasibility | Model | Status | Est. Cost |
|---|---|---|---|---|---|---|---|
| No experiments found | |||||||
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| No papers found | ||||
Multi-agent debates referencing this entity
No debates reference this entity