Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about P60484: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
No AI portrait yet
| Gene Symbol | P60484 |
| Protein Type | Phosphatase |
| Function | is a dual-specificity phosphatase that functions as a major negative regulator of the phosphatidylinositol-3-kinase (PI3K)/Akt signaling pathway. |
| Subcellular Localization | | Cytoplasm, nucleus, plasma membrane |
| Molecular Weight | 47 kDa |
| Amino Acids | 403 aa |
| GeneCards | P60484 |
| Human Protein Atlas | P60484 |
| Associated Diseases | neurodegeneration |
| Databases | GeneCardsUniProtNCBI GeneHPASTRING |
Knowledge base pages for this entity
graph TD
P60484["P60484"]
neurodegeneration["neurodegeneration"]
P60484 -->|"implicated_in"| neurodegeneration
style P60484 fill:#4a1a6b,stroke:#4fc3f7,stroke-width:2px,color:#e0e0e0| Target | Relation | Type | Str |
|---|---|---|---|
| No outgoing edges | |||
| Source | Relation | Type | Str |
|---|---|---|---|
| No incoming edges | |||
Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
|---|---|---|---|
| No targeting hypotheses | |||
Scientific analyses that reference this entity
No analyses mention this entity
Experimental studies targeting or related to this entity
| Experiment | Type | Disease | Score | Feasibility | Model | Status | Est. Cost |
|---|---|---|---|---|---|---|---|
| No experiments found | |||||||
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| No papers found | ||||
Multi-agent debates referencing this entity
No debates reference this entity
Hypotheses and analyses mentioning P60484 in their description or question text
No additional research found