PDE4B

protein-coding External Resolution
GeneCards NCBI PubMed

External Info (via mygene)

SymbolPDE4B
Namephosphodiesterase 4B
Typeprotein-coding
Sourcemygene

Summary

This gene is a member of the type IV, cyclic AMP (cAMP)-specific, cyclic nucleotide phosphodiesterase (PDE) family. The encoded protein regulates the cellular concentrations of cyclic nucleotides and thereby play a role in signal transduction. Altered activity of this protein has been associated with schizophrenia and bipolar affective disorder. Alternative splicing and the use of alternative promoters results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul

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