gene

PEO1

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about PEO1: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

0Connections
0Hypotheses
0Analyses
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0Experiments

Summary

Page for PEO1 Gene - Twinkle Mitochondrial DNA Helicase

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🧬 Gene Info
Gene SymbolPEO1
AliasesPage for PEO1 Gene
Chromosome10q24.31
FunctionThe PEO1 gene encodes a 684-amino acid hexameric helicase
Primary Expressionhigh-energy tissues:
Amino Acids684 aa
Ensembl IDENSG00000108018
GeneCardsPEO1
Human Protein AtlasPEO1
Associated Diseasesneurodegeneration
DatabasesGeneCardsUniProtNCBI GeneHPASTRING

Wiki Pages (10)

Knowledge base pages for this entity

Canonical Page

PEO1 Gene - Twinkle Mitochondrial DNA Helicase

gene · 659 words

Neural Circuits in Progressive Supranuclear Palsy

circuit · 2799 words

Mitochondrial Myopathy

disease · 1084 words

Progressive External Ophthalmoplegia

diseases · 1074 words

Twinkle (Mitochondrial DNA Helicase)

protein · 1035 words

TWNK Gene

gene · 759 words

Pathway Diagram

graph TD
    PEO1["PEO1"]
    neurodegeneration["neurodegeneration"]
    PEO1 -->|"implicated_in"| neurodegeneration
    style PEO1 fill:#4a1a6b,stroke:#4fc3f7,stroke-width:2px,color:#e0e0e0

Outgoing (0)

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No outgoing edges

Incoming (0)

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No incoming edges

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

HypothesisScoreDiseaseAnalysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Experiments (0)

Experimental studies targeting or related to this entity

ExperimentTypeDiseaseScoreFeasibilityModelStatusEst. Cost
No experiments found

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMIDAuthorsJournalYearCitations
No papers found