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gene 659 words KG: PEO1
Contents

PEO1 Gene - Twinkle Mitochondrial DNA Helicase

🧬 Gene Info
Gene SymbolPEO1
AliasesPage for PEO1 Gene
Chromosome10q24.31
FunctionThe PEO1 gene encodes a 684-amino acid hexameric helicase
Primary Expressionhigh-energy tissues:
Amino Acids684 aa
Ensembl IDENSG00000108018
GeneCardsPEO1
Human Protein AtlasPEO1
Associated Diseasesneurodegeneration
DatabasesGeneCardsUniProtNCBI GeneHPASTRING

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🌐 Cross-references

NCBI GeneUniProtGeneCardsWikipediaHGNCEnsembl

Related Hypotheses (15)

AMPK hypersensitivity in astrocytes creates enhanced mitocho
Score: 0.83CYP46A1 Overexpression Gene Therapy
Score: 0.77Senescent Cell Mitochondrial DNA Release
Score: 0.74Near-infrared light therapy stimulates COX4-dependent mitoch
Score: 0.74TFAM overexpression creates mitochondrial donor-recipient gr
Score: 0.73Mitochondrial Transfer Pathway Enhancement
Score: 0.70Astrocytic Lipoxin A4 Pathway Restoration via ALOX15 Gene Th
Score: 0.69RAB27A-dependent extracellular vesicle engineering for mitoc
Score: 0.67Mitochondrial-Lysosomal Contact Site Engineering
Score: 0.67GAP43-mediated tunneling nanotube stabilization enhances neu
Score: 0.67Mitochondrial RNA Granule Rescue Pathway
Score: 0.66Mitochondrial Calcium Buffering Enhancement via MCU Modulati
Score: 0.65Mitochondrial SPM Synthesis Platform Engineering
Score: 0.65Designer TRAK1-KIF5 fusion proteins accelerate therapeutic m
Score: 0.62CX43 hemichannel engineering enables size-selective mitochon
Score: 0.57

Related Analyses (11)

RNA binding protein dysregulation across ALS FTD and AD
neurodegeneration · archivedAutophagy-lysosome pathway convergence across neurodegenerat
neurodegeneration · archivedMitochondrial transfer between astrocytes and neurons
neurodegeneration · archivedSenolytic therapy for age-related neurodegeneration
neurodegeneration · archivedNeuroinflammation resolution mechanisms and pro-resolving me
neurodegeneration · archived

See Also (1)

Neurodegeneration
disease · KG edge: implicated_in

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