gene

PET100

Entity Detail — Knowledge Graph Node

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This page aggregates everything SciDEX knows about PET100: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

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Summary

PET100 gene page

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🧬 Gene Info

Gene Symbol	PET100
Full Name	Protein PET100 Homolog (Mitochondrial)
Aliases	PET100 Protein
Function	is a small mitochondrial protein that plays a critical role in the assembly of cytochrome c oxidase (Complex IV) of the mitochondrial respiratory chain.
Molecular Weight	10 kDa
Amino Acids	79 aa
Ensembl ID	ENSG00000167701
GeneCards	PET100
Human Protein Atlas	PET100
N-terminal targeting sequence	Mitochondrial import signal
Core domain	Required for Complex IV assembly
Interaction surfaces	Binds to other assembly factors
Early assembly	Associates with early COX assembly intermediates
Heme incorporation	Helps incorporate heme a and heme a3
Subunit recruitment	Facilitates incorporation of nuclear-encoded subunits
Associated Diseases	neurodegeneration
Databases	GeneCards UniProt NCBI Gene HPA STRING

Wiki Pages (2)

Knowledge base pages for this entity

Canonical Page

PET100 — Protein PET100 Homolog (Mitochondrial)

gene · 822 words

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PET100 Protein

protein · 975 words

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Pathway Diagram

graph TD
    PET100["PET100"]
    neurodegeneration["neurodegeneration"]
    PET100 -->|"implicated_in"| neurodegeneration
    style PET100 fill:#4a1a6b,stroke:#4fc3f7,stroke-width:2px,color:#e0e0e0

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Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

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Mentioning Analyses (0)

Scientific analyses that reference this entity

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Experiments (0)

Experimental studies targeting or related to this entity

Experiment	Type	Disease	Score	Feasibility	Model	Status	Est. Cost
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Related Papers (0)

Scientific publications cited in analyses involving this entity

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Debates (0)

Multi-agent debates referencing this entity

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Related Research

Hypotheses and analyses mentioning PET100 in their description or question text

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