gene 822 words KG: PET100 2026-03-11
kind:genesection:genesstate:published
Contents

PET100 — Protein PET100 Homolog (Mitochondrial)

🧬 Gene Info
Gene SymbolPET100
Full NameProtein PET100 Homolog (Mitochondrial)
AliasesPET100 Protein
Functionis a small mitochondrial protein that plays a critical role in the assembly of cytochrome c oxidase (Complex IV) of the mitochondrial respiratory chain.
Molecular Weight10 kDa
Amino Acids79 aa
Ensembl IDENSG00000167701
GeneCardsPET100
Human Protein AtlasPET100
N-terminal targeting sequenceMitochondrial import signal
Core domainRequired for Complex IV assembly
Interaction surfacesBinds to other assembly factors
Early assemblyAssociates with early COX assembly intermediates
Heme incorporationHelps incorporate heme a and heme a3
Subunit recruitmentFacilitates incorporation of nuclear-encoded subunits
Associated Diseasesneurodegeneration
DatabasesGeneCardsUniProtNCBI GeneHPASTRING

Knowledge Graph

Related Hypotheses (15)

AMPK hypersensitivity in astrocytes creates enhanced mitocho
Score: 0.57
Senescent Cell Mitochondrial DNA Release
Score: 0.54
Near-infrared light therapy stimulates COX4-dependent mitoch
Score: 0.51
Heat Shock Protein 70 Disaggregase Amplification
Score: 0.51
TFAM overexpression creates mitochondrial donor-recipient gr
Score: 0.47

Related Analyses (13)

Astrocyte reactivity subtypes in neurodegeneration
neurodegeneration · archived
Autophagy-lysosome pathway convergence across neurodegenerat
neurodegeneration · archived
Senolytic therapy for age-related neurodegeneration
neurodegeneration · archived
Neuroinflammation resolution mechanisms and pro-resolving me
neurodegeneration · archived
RNA binding protein dysregulation across ALS FTD and AD
neurodegeneration · archived

See Also (1)

Neurodegeneration
disease · KG edge: implicated_in