PEX13

Understanding Entity Pages

This page aggregates everything SciDEX knows about PEX13: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

Summary

PEX13 encodes peroxin-13, a critical component of the peroxisomal import machinery essential for peroxisome biogenesis. Mutations cause peroxisome biogenesis disorders with severe neurological manifestations.

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flowchart TD
    N0["PEX13"]
    N1["BECN1"]
    N1 -->|"targets"| N0
    N2["CYP27B1"]
    N2 -->|"targets"| N0
    N3["GCLC"]
    N3 -->|"targets"| N0
    N4["PCBP2"]
    N4 -->|"targets"| N0
    N5["PPP1CA"]
    N0 -->|"targets"| N5
    N6["VPS29"]
    N0 -->|"targets"| N6
    N7["VPS35"]
    N0 -->|"targets"| N7
    N8["YBX1"]
    N0 -->|"targets"| N8
    N9["neurodegeneration"]
    N0 -->|"implicated in"| N9

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    class N0 gene
    class N1 gene
    class N2 gene
    class N3 gene
    class N4 gene
    class N5 gene
    class N6 gene
    class N7 gene
    class N8 gene