GCLC

Understanding Entity Pages

This page aggregates everything SciDEX knows about GCLC: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

Summary

GCLC is a gene implicated in neurodegeneration research. Key relationships include: activates, implicated in, regulates. Associated with Als, Autoimmune, Infection. Connected to 74 entities in the SciDEX knowledge graph.

View on Wiki →

graph TD
    GCLC["<b>GCLC</b>"]
    Inflammation{"Inflammation"}
    GCLC -->|"biomarker for"| Inflammation
    GCLC -->|"activates"| Inflammation
    Obesity{"Obesity"}
    GCLC -->|"activates"| Obesity
    GCLC -->|"associated with"| Inflammation
    Als{"Als"}
    GCLC -->|"activates"| Als
    Ms{"Ms"}
    GCLC -->|"activates"| Ms
    Oxidative_Stress(["Oxidative Stress"])
    GCLC -->|"biomarker for"| Oxidative_Stress
    GCLM["GCLM"]
    GCLC -->|"regulates"| GCLM
    HMOX1["HMOX1"]
    GCLC -->|"regulates"| HMOX1
    GENES["GENES"]
    GCLC -->|"biomarker for"| GENES
    NRF2["NRF2"]
    GCLC -->|"regulates"| NRF2
    TXNRD1["TXNRD1"]
    GCLC -->|"regulates"| TXNRD1
    NRF2 -->|"regulates"| GCLC
    NQO1["NQO1"]
    NQO1 -->|"regulates"| GCLC
    HMOX1 -->|"regulates"| GCLC
    TXNRD1 -->|"regulates"| GCLC
    GCLM -->|"regulates"| GCLC
    NQO1 -->|"activates"| GCLC
    TFRC["TFRC"]
    TFRC -->|"activates"| GCLC
    SLC7A11["SLC7A11"]
    SLC7A11 -->|"activates"| GCLC
    ERK["ERK"]
    ERK -->|"activates"| GCLC
    P38["P38"]
    P38 -->|"activates"| GCLC
    GPX4["GPX4"]
    GPX4 -->|"activates"| GCLC
    ACSL4["ACSL4"]
    ACSL4 -->|"activates"| GCLC
    style GCLC fill:#1a3a4a,stroke:#4fc3f7,stroke-width:3px,color:#e0e0e0