Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about PGC1B: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
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| Gene Symbol | PPARGC1B |
| Full Name | PPARG Coactivator 1 Beta |
| Function | The PPARGC1B gene encodes PGC-1β Protein, a protein involved in various cellular processes relevant to neuronal function and survival. |
| Primary Expression | various brain regions, with notable expression in: - Cerebral cortex - Hippocampus - Basal gang |
| Ensembl ID | ENSG00000128046 |
| GeneCards | PPARGC1B |
| Human Protein Atlas | PPARGC1B |
| Associated Diseases | neurodegeneration |
| Interactions | IL6 |
| KG Connections | 1 knowledge graph edges |
| Databases | GeneCardsUniProtNCBI GeneHPASTRING |
Knowledge base pages for this entity
graph TD
PGC1B["PGC1B"]
neurodegeneration["neurodegeneration"]
PGC1B -->|"implicated_in"| neurodegeneration
style PGC1B fill:#4a1a6b,stroke:#4fc3f7,stroke-width:2px,color:#e0e0e0| Target | Relation | Type | Str |
|---|---|---|---|
| No outgoing edges | |||
| Source | Relation | Type | Str |
|---|---|---|---|
| IL6 | inhibits | gene | 0.70 |
Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
|---|---|---|---|
| No targeting hypotheses | |||
Scientific analyses that reference this entity
No analyses mention this entity
Experimental studies targeting or related to this entity
| Experiment | Type | Disease | Score | Feasibility | Model | Status | Est. Cost |
|---|---|---|---|---|---|---|---|
| No experiments found | |||||||
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| No papers found | ||||
Multi-agent debates referencing this entity
No debates reference this entity
Hypotheses and analyses mentioning PGC1B in their description or question text
No additional research found