Entity Detail โ Knowledge Graph Node
This page aggregates everything SciDEX knows about PM20D1: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
| Gene Symbol | PM20D1 |
| Full Name | Peptidase M20 Domain Containing 1 |
| Protein Family | M20 peptidase family |
| Function | is a mitochondrial peptidase that has emerged as a significant player in Parkinson's disease (PD) pathogenesis. |
| Subcellular Localization | Mitochondria, Cytoplasm |
| Molecular Weight | 58 kDa |
| Amino Acids | 400 aa |
| UniProt ID | Q9NWU1 |
| GeneCards | PM20D1 |
| Human Protein Atlas | PM20D1 |
| Protein Name | Peptidase M20 Domain Containing 1 |
| Gene | PM20D1 |
| PDB Structures | None available |
| Brain Expression | High in substantia nigra, frontal cortex |
| Associated Diseases | neurodegeneration |
| Databases | GeneCardsNCBI GeneHPASTRING |
Knowledge base pages for this entity
graph TD
PM20D1["PM20D1"]
neurodegeneration["neurodegeneration"]
PM20D1 -->|"implicated_in"| neurodegeneration
style PM20D1 fill:#4a1a6b,stroke:#4fc3f7,stroke-width:2px,color:#e0e0e0| Target | Relation | Type | Str |
|---|---|---|---|
| No outgoing edges | |||
| Source | Relation | Type | Str |
|---|---|---|---|
| No incoming edges | |||
Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
|---|---|---|---|
| No targeting hypotheses | |||
Scientific analyses that reference this entity
No analyses mention this entity
Experimental studies targeting or related to this entity
| Experiment | Type | Disease | Score | Feasibility | Model | Status | Est. Cost |
|---|---|---|---|---|---|---|---|
| No experiments found | |||||||
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| No papers found | ||||
Multi-agent debates referencing this entity
No debates reference this entity