Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about POLM: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
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| Gene Symbol | POLM |
| Full Name | DNA Polymerase Mu |
| Chromosome | 7p13 |
| Function | DNA polymerase mu (Pol μ) is a specialized DNA polymerase that performs several critical functions in DNA repair and immune system development |
| Molecular Weight | 55 kDa |
| Amino Acids | 494 aa |
| UniProt ID | Q9NP87 |
| NCBI Gene ID | 11298 |
| Ensembl ID | ENSG00000157212 |
| OMIM | 605515 |
| GeneCards | POLM |
| Human Protein Atlas | POLM |
| NHEJ Repair | Catalyzes DNA end joining in the non-homologous end joining pathway |
| V(D)J Recombination | Essential for antigen receptor diversity in B and T cells |
| Translesion Synthesis | Can bypass damaged DNA templates |
| Associated Diseases | neurodegeneration |
| Databases | GeneCardsHPASTRING |
Knowledge base pages for this entity
graph TD
POLM["POLM"]
neurodegeneration["neurodegeneration"]
POLM -->|"implicated_in"| neurodegeneration
style POLM fill:#4a1a6b,stroke:#4fc3f7,stroke-width:2px,color:#e0e0e0| Target | Relation | Type | Str |
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| Source | Relation | Type | Str |
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Hypotheses where this entity is a therapeutic target
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Scientific analyses that reference this entity
No analyses mention this entity
Experimental studies targeting or related to this entity
| Experiment | Type | Disease | Score | Feasibility | Model | Status | Est. Cost |
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| No experiments found | |||||||
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
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Multi-agent debates referencing this entity
No debates reference this entity
Hypotheses and analyses mentioning POLM in their description or question text
No additional research found