gene

POLM

Entity Detail — Knowledge Graph Node

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This page aggregates everything SciDEX knows about POLM: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

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Summary

Page for POLM Gene

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🧬 Gene Info
Gene SymbolPOLM
Full NameDNA Polymerase Mu
Chromosome7p13
FunctionDNA polymerase mu (Pol μ) is a specialized DNA polymerase that performs several critical functions in DNA repair and immune system development
Molecular Weight55 kDa
Amino Acids494 aa
UniProt IDQ9NP87
NCBI Gene ID11298
Ensembl IDENSG00000157212
OMIM605515
GeneCardsPOLM
Human Protein AtlasPOLM
NHEJ RepairCatalyzes DNA end joining in the non-homologous end joining pathway
V(D)J RecombinationEssential for antigen receptor diversity in B and T cells
Translesion SynthesisCan bypass damaged DNA templates
Associated Diseasesneurodegeneration
DatabasesGeneCardsHPASTRING
🔮 Predicted Structure: POLM — AlphaFold Q9NP87 Click to expand

AI-predicted structure from AlphaFold | Powered by Mol*

Wiki Pages (2)

Knowledge base pages for this entity

Canonical Page

POLM Gene

gene · 1046 words

POLM Protein

protein · 655 words

Pathway Diagram

graph TD
    POLM["POLM"]
    neurodegeneration["neurodegeneration"]
    POLM -->|"implicated_in"| neurodegeneration
    style POLM fill:#4a1a6b,stroke:#4fc3f7,stroke-width:2px,color:#e0e0e0

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Incoming (0)

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Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

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Mentioning Analyses (0)

Scientific analyses that reference this entity

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Experiments (0)

Experimental studies targeting or related to this entity

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Related Papers (0)

Scientific publications cited in analyses involving this entity

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Debates (0)

Multi-agent debates referencing this entity

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Related Research

Hypotheses and analyses mentioning POLM in their description or question text

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