PPP3CB

protein-coding External Resolution
GeneCards NCBI PubMed

External Info (via mygene)

SymbolPPP3CB
Nameprotein phosphatase 3 catalytic subunit beta
Typeprotein-coding
Sourcemygene

Summary

Enables several functions, including calmodulin binding activity; calmodulin-dependent protein phosphatase activity; and protein phosphatase 2B binding activity. Involved in calcineurin-NFAT signaling cascade; positive regulation of transcription by RNA polymerase II; and protein dephosphorylation. Located in cytoplasm. Part of calcineurin complex. Implicated in aortic valve stenosis. Biomarker of focal segmental glomerulosclerosis and schizophrenia. [provided by Alliance of Genome Resources, Ap

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