| Gene Symbol | PPP3CB |
| Chromosome | 2p22.1 |
| Protein Type | Gene |
| Function | is an important component in the neurobiology of neurodegenerative diseases. |
| Molecular Weight | 61 kDa |
| Amino Acids | 524 aa |
| Pathways | Autophagy, Chaperone, Mtor, Tdp-43, autophagy pathway |
| UniProt ID | P16234 |
| NCBI Gene ID | 5519 |
| Ensembl ID | ENSG00000107738 |
| GeneCards | PPP3CB |
| Human Protein Atlas | PPP3CB |
| Calcineurin A (catalytic subunit) | 60-61 kDa protein with catalytic domain |
| Calcineurin B (regulatory subunit) | 19 kDa calcium-binding protein |
| N-terminal domain | Regulatory region with auto-inhibitory segment |
| Associated Diseases | Als, Amyotrophic Lateral Sclerosis, Ataxia, Huntington, Neuroblastoma |
| Known Drugs/Compounds | rapamycin |
| Interactions | amyotrophic lateral sclerosis, AR, ATG, ATG10, ATG12, AUTOPHAGY |
| KG Connections | 190 knowledge graph edges |
| Databases | GeneCardsHPASTRING |
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